Recent trends in global health financing indicate that funding levels by governments and donors may not be adequate to meet the health and well-being Sustainable Development Goals (SDGs). Blended finance - the strategic use of public and philanthropic resources to mobilize private capital to achieve development outcomes - can be an important tool to address the approximate $134 billion funding gap to achieve the health SDGs in low- and middle-income countries (2016 estimate). This document is a practical resource for USAID, other donors, and partners, and highlights findings from India, Tanzania, and Liberia on how to catalyze blended finance transactions. This resource was provided to members during the August 27, 2019 PSE Subgroup Meeting.